STINEE

Gariand C W, Nounesis G and Stine J J 1989 XY behavior for the heat-oapaoity at nematio-smeotio-A iiquid-orystai transitions Phys.Rev. A 39 4919-22... 

Removal of sulphur as sodium sulphide. Dissolve about 0 i g. of c> stine in a few ml. of 10% NaOH solution. Add a few drops of lead acetate solution and boil for 1 minute. The solution darkens owing to the formation of lead sulphide. 

Nitrosomethylurea. Acetamide method. To a solution of 59 g. of acetamide in 88 g. (28 ml.) of bromine (1) in a 4-litre beaker add dropwise, with hand stining, a solution of 40 g. of sodium hydroxide in 160 ml. of water. Heat the resulting yellow reaction mixture on a steam bath until eflfervescence sets in (2), after which continue the heating for 2-3 minutes. CrystaUisation of the product from the yellow or red coloured solution usually commences immediately. Cool in an ice bath for 1-2 hours, collect the product by suction filtration, wash with a little ice-cold water, and dry in the air. The yield of colourless acetylmethylurea, m.p. 178-180°, is 50 g. 

M. M. Stine and L. A. Strety, "Sensitivity and Performance Characteri2ation of DINGO," in Eighth Symposium (International) on Detonation,... 

The new /-hydrastine is considered to be /-a-hydrastine and natural hydrastine to be /- -hydrastine, which implies (1) that the latter differs from natural narcotine (/-a-narcotine) in stereochemical configuration (2) that since a-gnoscopine, but not -gnoscopine, can be resolved, the synthesis of natural hydrastine will involve the deracemisation of hydra-stine-b, to /-a-hydrastine, which can be epimerised to natural hydrastine (/- -hydrastine) by boiling with methyl-alcoholic potassium hydroxide. 

The. structure.s of vinbla.stine, vincri.stine, colchicine, and taxol. 

A mixture of l,4-dibromo-2,5-bis(3-sulfonatopropoxy)benzene 61 (0.78 g, 1.39 mmol), 60 (0.23 g, 1.39 mmol), Na2C03 (0.99 g) in doubly distilled water (47 mL), and DMF (20 mL) was heated at 85°C until the solids were completely dissolved. The resulting solution was cannulated to a 200-mL Schlenk flask with tris[(sulfonatophenyl)phosphine]palladium(0) (0.045 g) and the mixture was stined at 85°C for 10 h. The reaction mixture was concentrated to 25 mL by boiling and filtered. The filtrate was added dropwise to cold acetone (250 mL) to precipitate out the polymer. The polymer was collected by filtration, redissolved in a minimum of hot water, and reprecipitated by cooling. After repeating this procedure twice, the polymer was redissolved in distilled water and dialyzed for 72 h in 3500 gmol 1 cutoff membrane. After drying under vacuum, polymer 63 was obtained in 64% (0.42 g). 

Gerstein M. and Stine W.B., Analytical criteria for flammability limits, Proc. Combust. Inst., 14 1109-1118, 1973. 

KEITH J. STINE University of Missouri-St. Louis, St. Louis, Missouri... 

---