Star fruit juice

Fang HC et al [24] in their report intended to establish a connection between star fruit and acute oxalate nephropathy. They administered star fruit juice, 4 mL/100 g of body weight, in male Sprague-Dawley rats of 180 to 200 g, with an oxalate concentration of 2.4g/dL, approximately 1 g/kg. The authors established a strong relationship between star fruit and acute oxalate nephropathy. This relationship was found only in the experimental group under both fasting and water deprivation conditions. 

Although there are not many other cases of star fruit oxalate nephrotoxicity described, it seems reasonable to avoid consumption of large amounts of star fruit juice especially on an empty stomach and chronic consumption in patients with underlying chronic renal disease. 

Figure 2. Examples of chemical constituents presenting on star fruit juice.

A preliminary characterization of the video-EEG after crude star fruit juice had been given to animals... 

Star fruit juice also induced seizures when applied to cortical areas, showing that convulsant activity is present in crude star fruit extracts. The present data confirm the excitatory profile of AcTx and star fruit extracts. The progressive and sustained EEG epileptiform activity induced by AcTx is a characteristic of known... 

Drug-food interactions A systematic review evaluating interactions between CBZ and food [60 ] found that caffeine decreases oral bioavailability and impairs the anticonvulsant efficacy of CBZ in both human and animal studies. Grapefruit, kinnow, pomegranate, and star fruit juices cause an increase in the oral bioavailability of CBZ through inhibition of enteric CYP3A4 activity. 

Figure 5 Verification of a fruit juice sample (rediluted apple juice from Poland). Left the 400 MHz H spectrum in the region near 2 ppm (black trace) is plotted over a quantiles plot (gray-scale) of the model spectra set (univariate analysis of apple juice at 2 ppm). Right influence plot of a multivariate analysis (circles reference samples star test sample green region representative of group red region not representative).

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