Staphylokinase aureus

Staphylokinase (extracted from Staphylococcus aureus and produced in various recombinant systems Various... [Pg.346]

Kim, S.H., et ah, A novel variant of staphylokinase gene from Staphylococcus aureus ATCC 29213. Thromb Res 1997, 87, 387-395. [Pg.399]

Staphylocoagulase, prethrombin-2 complex 387 Staphylocoagulase SC 386 Staphylococcus aureus 1129, 1350 Staphylokinase, plasminogen complex 384 Staphylokinase (SAK) 381, 383 STAT-1 233 STAT-3 233... [Pg.1880]

Jin T, Bokarewa M, Foster T et at Staphylococcus aureus resists human defensins by production of staphylokinase, a novel bacterial evasion mechanism. J Immunol 2004 172 1169-1176. [Pg.31]

Another way for S. aureus to inhibit phagocytosis is via the production of Staphylokinase (SAK) (16 kDa). SAK targets plasminogen (PLG) on the bacterial sur ce and activates it into plasmin (PL). PL can cleave two major opsonic molecules, IgG (at the hinge region) and C3b. It was shown that the conversion of PLG to PL by SAK leads to removal of IgG and C3b on the bacterial surface. Thus, SAK impairs both IgG and complement dependent phagocytosis by human neutrophils. ... [Pg.36]

II, Pseudocollagenase (Clostridium) Thermolysin (Bacillus subtilis)] Protease III, Staphylokinase (Staphylococcus aureus)-, Coccus P(Proteinase) (Serratia)-, Pronase component (Streptomyces griseus)-, P. roqueforti protease II ... [Pg.230]

Tinoco, P. N. Borer, B. Dengler, M. D. Levine, 0. C. Uhlenbeck, D. M. Crothers and J. Gralla, Improved Estimation of Secondary Structure in Ribonucleic Acids, Nature (New Biol.), 246 40-41 (1973). Sako and N. Tsuchida, Nucleotide Sequence of the Staphylokinase Gene from Staphylococcus aureus, Nucl. Acids Res., 11 7679-7693 (1983). [Pg.38]

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