Stannatranes complexes

A rare case of the formation of the first metal-bound stannatrane complex 187 has been reported as the result of the reaction between triethanolamine and organometallic compound 186 (Equation 11) <1999CC837>. As confirmed by a X-ray single crystal diffraction study, the Sn-N distance is significantly shorter compared to the sum of the tin(iv) and nitrogen van der Waals radii. 

The first stannatrane containing a tin-metal bond, the osmium derivative 450, was synthesized from TEAA and a triiodostannyl osmium complex (Scheme 20)878. 

The pyridine-based stannatrane (166) can be prepared from Bu°2SnO and 2,6-(CH20H)2 pyridine." " Aldimino alcohols react with Bu°2Sn(NMe2)2 to form initially A,0-chelated complexes that quickly dimerize to give five-coordinate geometries such as (167)." ... 

Process research efforts relative to the design of a practical synthesis of a structurally complex MRSA carbapenem (1) culminated in the establishment of two distinct synAeses. The first is based on a unique Stille coupling between a carbapenem enol triflate and a stannatrane appended via a methylene spacer to a complex and extended heteroaromatic side chain. The second is founded upon a novel n-allyl palladium reaction to incorporate die entire complex side chain. Details on die development of both methods are described. 

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