Stagnant Loop Syndrome

The serum bile salt pattern is altered in patients with bacterial proliferation in the small intestinal content (stagnant loop or blind loop syndrome). Bacterial deconjugation of bile salts in the lumen of the small intestine per- 

In circumstances where there is a stagnant loop or shortened bowel, bile salt patterns in serum reflect those found in the intestinal content (78). 

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Jones EA, Craigie A, Tavill AS, Franglen G, RosenoerVM Protein metabolism in the intestinal stagnant loop syndrome. Gut 1968 9 466-469. 

Deconjugation of bile acids may become excessive when bacterial overgrowth occurs in the small intestine. This condition is referred to as the stagnant loop or blind loop syndrome and is characterized by diarrhea, often accompanied by steatorrhea because of a decrease in the effective concentration of conjugated bile salts and a reduction in the fat-absorptive capacity of the small intestine. 

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