Squibb Diagnostics

Choletec package insert, 2000, Squibb Diagnostics, Inc., Princeton, NJ. 

Fig. 26 1. Electron micrograph of Coxiella burnetii in the phagolysosome of an infected yolk sac cell, demonstrating both large (LCV) and small (SCV) cell variants. The bar in the lower right corner represents 0.6 pm. After Renografin (manufactured by Squibb Diagnostics, Princeton, NJ) purification, the cells were fixed with primary fixative and stained with potassium permanganate. The phagolysosome contains many pleomorphic C burnetii organisms. Multiplication by binary transverse fission with septa formation (arrows) is seen.

Another diagnostic kit for the preparation of Tc-sestamibi is Miraluma, approved for breast imaging (Bristol-Myers Squibb 2001). 

RENO M 60 Renocal Renograffin M-76 Renogratin Renovist Renurix Sinografin Unipaque Urovist. Diagnostic aid. Crystals mp = 189-193° soluble in H2O (89 g/100 ml). Bristol-Myers Squibb Co. 

A first application of the new, very efficient asymmetric synthesis of C2-sym-fnetric ketones is described in scheme 7. Since the Center for Disease Control in Atlanta (USA) defined the diagnostic term AIDS (Acquired Immunodeficiency Syndrome) in 1982 [24] only three medications have been authorized for treatment of AIDS 3 -azido-3 -deoxythymidine (AZT, Wellcome, 1987), 2 ,3 -dideoxyinosine (DDI, Bristol Myers Squibb, 1992), and 2 ,3 -dideoxycytosine (DDC, Hoffmann La Roche, 1992), which was recently introduced for limited use. These drugs inhibit the enzyme reverse transcriptase of the human immunodeficiency virus (HIV). Nevertheless, they are only able to prolong somewhat the survival of patients with advanced cases of AIDS. They also lead to considerable side-effects (bone marrow damage, neuropathy) and to the generation of more resistant strains of the virus [25]. 

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