Sporidiobolus salmonicolor

Reduction of ethyl 2 -ketopantothenate to ethyl 2 -d-pantothenate ((g) in Fig. 8). The rate of condensation of ketopantolactone or D-pantolactone with ethyl (3-alanine, yielding ethyl 2 -ketopantothenate (0 in Fig. 8) or ethyl D-panto-thenate, respectively, is quite fast compared to the condensation of ketopantolactone or D-pantolactone with (3-alanine, and the reaction with ethyl (3-alanine proceeds more stoichiometrically [117]. Since the enzymatic hydrolysis of ethyl D-pantothenate has been established [118], if the stereoselective reduction of ethyl 2 -ketopantothenate to ethyl D-pantothenate is possible, both the troublesome resolution and the incomplete condensation might be avoided at the same time. Carbonyl reductase of C. macedoniensis is used for this purpose. Washed cells of the yeast converted ethyl 2 -ketopantothenate (80 g/1) almost specifically to ethyl D-pantothenate (> 98% e.e.), with a molar yield of 97.2% [103]. In a similar manner, 2 -ketopantothenonitrile (50 g/1) was converted to D-pan-tothenonitrile (93.6% e.e.), with a molar yield of 95.6%, on incubation with Sporidiobolus salmonicolor cells as a catalyst [104],... 

In situ detoxification of the fermentation medium during gammadecalactone production with the yeast Sporidiobolus salmonicolor. Biotechnol. Progr., 15,... 

L., and Voilley, A. (1998) Trapping of gamma-decalactone by adsorption on hydrophobic sorbents application to the bioconversion of methyl ricinoleate by the yeast Sporidiobolus salmonicolor. Biotechnol. Tech., 12, 109-113. 

Lee, S., Cheng, H., Chen, W., and Chou, C. (1998) Production of gammadecalactone from ricinoleic acid by immobilized cells of Sporidiobolus salmonicolor. Process Biochem., 33,... 

Sporidiobolus salmonicolor Vinasse and ricinoleic acid methyl ester Billerbeck et al. (2003)... 

Lee S-L, Lin S-J, Chou C-C (1995) Growth of and production of y-decalactone by Sporobolomyces odorus in jar fermentors as affected by pH, aeration and fed-batch technique. J Ferment Bioeng 80(2) 195-199. doi 10.1016/0922-338x(95)93219-a Lee S-L, Cheng H-Y, Chen W-C, Chou C-C (1998) Production of y-decalactone from ricinoleic acid by immobilized cells of Sporidiobolus salmonicolor. Process Biochem 33(4) 453-459. doi 10.1016/s0032-9592(98)00013-2... 

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