Spontaneous bowel movements

Drug-specific antibodies of the IgE type combine via their Fc moiety with receptors on the surface of mast cells. Binding of the drug provides the stimulus for the release of histamine and other mediators. In the most severe form, a life-threatening anaphylactic shock develops, accompanied by hypotension, bronchospasm (asthma attack), laryngeal edema, urticaria, stimulation of gut musculature, and spontaneous bowel movements (p. 326). 

After this period, the program can be modified every other day. If the patient does not have a bowel movement, then it may be necessary to change the routine every third day or three times a week. A spontaneous bowel movement that occurs close to the rectal stimulant is a sign that the reflex response and muscle control are improving. In this situation, the rectal medication should be held to see if the patient would continue to have spontaneous... 

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