Sponges Luffariella variabilis

Phospholipase A2 Manoalide (Structure 16.5) majuscida Sponge, Luffariella variabilis Anti-inflammatory16... 

However, clinical studies on marine metabolites are often hampered by insufficient supply of material, as it was reported for dolastatin 10 from the sea hare Dolabella auricularia [107]. In the case of manoalide, obtained from the sponge Luffariella variabilis, it remains open whether its use will be restricted to an application in studying inflammatory processes on the cell level or whether it... 

Manoallde. C2jH3603, Mr 416.56, amorphous solid, as 25-acetate mp. 117 -119 °C. A sesterterpenoid marine natural product from the sponge Luffariella variabilis, the name is derived from the Manoa valley, Oahu, Ha-... 

De SUva, E.D., Scheuer, P.J., 1980. ManoaUde, an antibiotic sesterterpenoid from the marine sponge Luffariella variabilis. Tetrahedron 21,1611-1614. 

De Silva, E.D., and P.J. Scheuer Manoalide, an Antibiotic Sesterterpenoid from the Marine Sponge Luffariella variabilis (Polejaeff). Tetrahedron Lett. 21, 1611 (1980). 

Gauvin, A., Smadja, J., Aknin, M., Faure, R., and Gaydou, E.M. (2000) Isolation of bioactive 5a,8a-epidioxy sterols from the marine sponge Luffariella( . variabilis. Can.]. Chem., 78, 986-992. 

Motti, C.A., Fttinger-Fpstein, P., Willis, R.H., and Tapiolas, D.M. (2010) ESI FTIR-MS analysis of larvae from the marine sponge Luffariella variabilis. Mar. Drugs, 8, 190-199. 

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