Split/4 problem

Analyse by splitting problems. Figure 4-11 shows some splits we have considered here. 

Split Problem -- Existing Ideas New Ideas Mind Map of Ideas ... 

Note that, aside from the splitting problem, the i.d. reduction of LC columns leads to a sensible increase in sensitivity of the LC/ESI/MS system. In fact, as shown schematically in Fig. 1.9, the i.d. reduction leads to a higher analyte concentration, due to the volume reduction Then, passing from a 4.6 to a 1.5 mm i.d. column, a decreased volume of one order of magnitude is obtained. This result reflects in a 10 times increase of analyte concentration and the consequent increase of the MS signal. 

Acknowledgements. The author wishes to thank his collaborators in the joint research referred to in this chapter. In particular he has benefit-ted from O.K. Andersen s expertise on his linear methods (LMTO, LAPW), from the extensive collaboration with M. Cardona on the electronic structures on semiconductors, not least the spin-splitting problems. R.C. Albers, M. Boring and G. Zwicknagl are thanked for their collaborations on the relativistic electronic structures of heavy-fermion materials, and A. Svane and L. Petit for several discussions and valuable information on their progress in the description of strongly correlated electron systems. 

Equation 7.36 is only valid for sharp split problems. This is quite a remarkable outcome, because it means at sharp split conditions, one has to operate on the A7 = 0 line in Figure 7.44 regardless of the value of R i or the feed composition. Conversely, it can be said that if the vapor and liquid flowrates in CS7 are not kept equal to each other, a sharp split will never be obtained. This is true regardless of the thermodynamic properties of the system. 

Grishanov S A and Vassihev V A (2011), Invariants of links in 3-manifolds and splitting problem of textile structures , I Knot Theor Ramif, 20(3), 345-370. 

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