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Sphingosine lymphocytes

Brinkmann V, Cyster JG, Hla T (2004) FTY720 sphingosine 1-phosphate receptor-1 in the control of lymphocyte egress and endothelial barrier function. Am J Transplant 4 1019-1025... [Pg.715]

CuvUlier, O., Rosenthal, D.S., Smulson, M.E. and Spiegel, S., 1998, Sphingosine 1-phosphate inhibits activation ofcaspases that cleave poly(ADP-ribose)polymerase and lamins during Fas- and ceramide-mediated apoptosis injurkat T lymphocytes,/. Biol. Chem. 273 2910-2916. [Pg.261]

Chiba, K. 2005. FTY720, a new class of immunomodulator, inhibits lymphocyte egress from secondary lymphoid tissues and thymus by antagonistic activity at sphingosine 1-phosphate receptors. Pharmacology and Therapeutics, 108 308-319. [Pg.256]

Apart from PKA, some other protein-kinases were found to be controlled by forskolin, such as cytosolic sphingosine kinase in rat periosteal cells [186] and protein kinase B (PKB) [187]. The latter was found to be stimulated by the activation of PKA through a PI3 (phosphatidylinositol 3)-kinase-independent pathway. Furthermore, a distinct activation mechanism was suspected, other than that normally observed by growth factors such as insulin, since substitution of the serine at the S473 position of PKB with alanine could not prevent activation by forskolin. The JAK family of protein kinases in T lymphocytes can also be regulated by forskolin through the activation of PKA [188]. Thus it seems obvious that many other enzymes could be susceptible to control by forskolin. [Pg.264]

Mandala S, Hajdu R, Bergstrom J, Quackenbush E, Xie J, Milligan J, Thornton R, Shei GJ, Card D, Keohane C, Rosenbach M, Hale J, Lynch CL, Rupprecht K, Parsons W, Rosen H (2002) Alteration of lymphocyte trafficking by sphingosine-1-phosphate receptor agonists. Science 296 346-349... [Pg.44]

Sanna MG, Liao J, Jo E, Alfonso C, Ahn MY, Peterson MS, Webb B, Lefebvre S, Chun J, Gray N, Rosen H (2004) Sphingosine 1-phosphate (SIP) receptor subtypes SlPl and S1P3, respectively, regulate lymphocyte recirculation and heart rate. J Biol Chem 279 13839-13848... [Pg.45]

W., and Rosen, H, (2002) Alteration of lymphocyte trafficking by sphingosine-1-phosphate receptor agonists. Science,... [Pg.61]

Mandala, S, Hajdu, R, Bergstrom, J, Quackenhush, E, Xie, J, Milligan, J, Thornton, R, Shei, GJ, Card, D, Keohane, C, Rosenbach, M, Hale, J, Lynch, CL, Rupprecht, K, Parsons, W and Rosen, H (2002) Alteration of lymphocyte trafficking by sphingosine 1-phosphate receptor agonists. Science, 296, 346-349. [Pg.103]

See other pages where Sphingosine lymphocytes is mentioned: [Pg.103]    [Pg.105]    [Pg.127]    [Pg.245]    [Pg.247]    [Pg.250]    [Pg.412]    [Pg.27]    [Pg.95]    [Pg.178]    [Pg.1774]    [Pg.447]    [Pg.291]    [Pg.292]    [Pg.294]    [Pg.515]    [Pg.519]    [Pg.917]    [Pg.54]    [Pg.56]    [Pg.60]    [Pg.60]    [Pg.91]    [Pg.616]    [Pg.332]   
See also in sourсe #XX -- [ Pg.255 ]



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