Spectroscopic Probes of Surfactant Systems and Biopolymers

A fascinating aspect of surfactant systems resides in the fact that within the same chemical system one-dimensional aggregates (rod-like micelles), two-dimensional bilayers, and space-filling continuous structures may be formed. This aspect of dimensionality has been probed by studying the time-dependence of fluorescence, as induced by lipophilic quencher molecules diffusing within dimensionally restricted regions of space. 

The second part of this study was devoted to the spectroscopic probing of biopolymers. Transitions between right and left-helical conformations of oligonucleotide duplexes were monitored by Raman and 2D NMR techniques. 

Macromolecular Systems Microscopic Interactions and Macroscopic Properties Deutsche Forschungsgemeinschaft (DFG) 

Copyright 2000 WILEY-VCH Verlag GmbH, Weinheim. ISBN 978-3-527-27726-1 

The conditions for the applicability of surface enhanced Raman spectroscopy for studies of oligo and polynucleotides has been assessed. In particular, surface enhanced resonance Raman spectroscopy (SERRS) has been used to study the binding of chromophores to DNA strands at probe concentrations as low as 10 M. 

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