Specific enol equivalents Wittig reagents

Specific enol equivalents will be needed for both synthons (61) and (66), Since (61) is to give a double bond but (66) is to give an alcohol, the logical choices are a Wittig reagent - actually (67) - for (61) and a Reformatsky reagent for (66). The ester to aldehyde conversion (65 63) Is easiest by over-reduction and re-... [Pg.229]

Conjugated Wittig reagents as specific enol equivalents... [Pg.700]

When the Wittig reaction was introduced (Chapter 14) we saw it simply as an alkene synthesis. Now if we look at one group of Wittig reagents, those derived from a-halo-carbonyl compounds, we can see that they behave as specific enol equivalents in making unsaturated carbonyl compounds. [Pg.700]

We have already met one series of specific enol equivalents as Wittig reagents (66) may be used in this way (see Chapter 15). [Pg.170]

The first is an a,p-unsaturated carbonyl compound and can best be made by an aldol reaction using some sort of specific enol equivalent for the add part. A Wittig reagent, a malonate, or a silyl enol ether look the best. [Pg.300]

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