Space-Charge-Induced Matrix Interferences

There are a number of ways to compensate for space charge matrix suppression in ICP-MS. IS has been used, but unfortunately does not address the fundamental cause of the problem. The most common approach used to alleviate or at least reduce space charge effects is to apply voltages to individual lens components of the ion optics. This is achieved in a number of different ways, but irrespective of the design of the ion-focusing system, its main function is to reduce matrix-based suppression 

FIGURE 14.6 Space charge matrix suppression caused by 1000 ppm uranium is significantly higher on low-mass elements such as Li and Be than it is with the high-mass elements such as T1 and Pb. (From S. D. Tanner, Journal of Analytical Atomic Spectrometry, 10, 905, 1995.) 

UIPAC Isotopic Composition of the Elements, Pure and Applied Chemistry 75(6), 683-799, 2003. 

Collard, K. Kawabata, Y. Kishi, and R. Thomas, Micro, January 2002. 

Titles, N. Jakubowski, and D. Stuewer, Poster Presentation at Winter Conference on Plasma Spectrochemistry, San Diego, 1994. 

There are a number of ways to compensate for space-charge matrix suppression in ICP-MS. IS has been used but unfortunately does not address the fundamental cause 

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