Sorting nexin 9 interactions

Fig. 2. Novel receptor-interacting partners of selected 5-HT receptors, their interaction domains on the receptors, and consequences of the interactions. Abbreviations CaM, Ca2+/calmodulin PDZ, a protein interaction domain termed postsynaptic density 95/discs large/ZO-1 PSD-95, a key protein component of the excitatory postsynaptic density MUPP1, multi-PDZ-domain protein SNX27a, a member of the new sorting nexin family of proteins NHERF, NHE regulatory factor. MUPP1 prevents phosphorylation of serine-458 of the 5-HT2C receptor.

Joubert L, Hanson B, Barthet G, et al. New sorting nexin (SNX27) and NHERF specifically interact with the 5-E n 4u receptor splice variant roles in receptor targeting. J Cell Sci 2004 117 5367-5379. 

Lundmark, R., and Carlsson, S. R. (2003). Sorting nexin 9 participates in clathrin-mediated endocytosis through interactions with the core components. J. Biol. Chem. 278, 46772-46781. 

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