Some models of metalloenzymes

Lately, extensive research has been devoted to metalloenzymes. Thus, carbonic anhydrase is a very effective catalyst for conversion of CO2 to carbonic acid (H2CO3), and vice versa This enzyme is found in red blood cells, gastric mucosa, pancreatic cells, and renal tubules. Carbonic anhydrase plays an important role in respiration by influencing CO2 transport in the blood. The enzyme also functions in the formation of hydrochloric acid by the stomach. 

Kaim and B. Schwederski, Bioinorganic Chemistry Inorganic Elements in the Chemistry of Life, Wiley, New York 1991, pp. 24, 66, 88-100, 117, 335. 

Edwards, Inorganic Reaction Mechanisms, W. A. Benjamin, New York 1964, p. 53ff. 

Lever and D. B. Gray, Iron Porphyrins, Parts 1 and 2, Addison-Wesley, Reading, 

Antonini and M. Brunori, Hemoglobins and Myoglobins in their Reactions with Ligands, North-Holland, Amsterdam 1971. 

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