Solvent-Free C-N Bond Formation under Microwave Irradiation

2 Solvent-Free C-N Bond Formation under Microwave Irradiation [Pg.244]

Type of reaction C-N bond formation Reaction condition solvent-free [Pg.244]

Keywords 4,6-dimethyl-1,2,3-triazine, enamine, Diels-Alder reaction, N2 elimination, microwave irradiation, pyridine derivative [Pg.244]

A mixture of triazine and enamine (2 1 molar ratio) was irradiated at atmospheric pressure in a focused microwave reactor (Prolabo MX350) at 270 W for 20 min (max. temperature 150 °C). The crude reaction mixture was purified by flash chromatography on silica gel (Merck type 60, 230-400 mesh). [Pg.245]

References A. Diaz-Ortiz, A. de la Hoz, P. Pieto, J.R. Carrillo, A. Moreno, H. Neun-hoeffer, Synlett, 236 (2001). [Pg.245]

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