Solvent Effects on Values

Investigate the effect of changing the ratios of the two solvents used for the separation of the 1,2-cyclohexanediols on the f /-values for the diastereomers. One way to report the relative effeotiveness of various solvent mixtures in effeoting the separation would be to report values of AR for each mixture used. Consult with your instructor before carrying out any experiments. 

Transfer any excess of the eluting solvents to a container for nonhalogenated organic liquids. Dispose of the used TIC plates in a container for nonhazard ous materials. 

The maximum number of stereoisomers that are possible for a given molecule can be determined from the formula 2 , where n is the number of stereocenters in the molecule. 

A meso compound is achiral by virtue of the fact that it contains an internal mirror plane of symmetry, so the molecule is superimposable on its mirror image and hence does not have an enantiomer. Use a dashed line to show the internal plane of symmetry present in the structure of ds-l,2-cyclohexanediol (6). 

Indicate the stereochemical relationship (i.e., enantiomers or diastereomers) between each of the following pairs of stereoisomers of 1,2-dibromocyclohexane, and indicate whether each pair will have identical or different physical properties. 

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Table 1 Solvent effects on values of effective molarity [M] ...

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