Solid-Phase Methods for Purification of Synthesized Oligosaccharides

4 Solid-Phase Methods for Purification of Synthesized Oligosaccharides 

OLIGOSACCHARIDE SYNTHESIS ON SOLID, SOLUBLE POLYMER, AND TAG SUPPORTS 

Compound 72 was then successfully captured by theFmoc-cystein-loaded Wang resin at the ClAc tag in the presence of diisopropylethylamine (DIPEA). After washing the resin, 73 was released from the resin by Fmoc deprotection with 4-(aminomethyl)piperidine followed by the spontaneous intramolecular cyclization to afford 74 with excellent purity 

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