Solid phase absorptiometry

An excellent example of solid phase absorptiometry through analyte derivatization by on-column reaction with a immobilized reagent is that reported by ValcarceFs group 

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Grate, J. W., Egorov, O., O Hara, M. J., and DeVol, T. A., Radionuclide sensors for environmental monitoring From flow injection solid phase absorptiometry to equilibration-based preconcentrating minicolumn sensors with radiometric detection, Chem. Rev., 108, 543-563, 2008. 

It is worth noticing that apparently all the three reported methods did not suffer from interferences due to refractive index variations. Although this is an advantage in common with solid phase absorptiometry, the magnitude of interference, if any, appears to be even less than the latter. 

Chromium(VI) was determined in fresh water samples using solid phase absorptiometry. The complex of chromium(VI) with 1,5-diphenylcafbazide was sorbed on a cation exchanger packed in a flow-cell. The detection limit was as low as 33 ng 1 [12]. 

Phosphate was determined in rain water, sea water and ground water at //g 1 " levels by Yoshimura et al.[22] using solid phase absorptiometry. The ion-associate formed by the reaction of molybdophosphate with Malachite Green was sorbed on a Sephadex dextran gel packed in a ilow-cell, and the increase in absorbance was monitored to perform the determination of phosphate, resulting in a very sensitive method. 

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