Sodium nitrile

The degradation of polymers may be prevented by the addition of sodium nitrile, thiourea, etc. 

Other Tests. Thr other tests mid the < uiiuliiiitive determination given under Sodium Nitrile should aln In made observing the conditions there desriilted. 

By interaction of 7-amino-8-oxo-3-vinyl-5-thia-l-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid 4-methoxyphenyl ester with 4-bromoacetyl bromide was prepared 7-(4-bromo-3-oxo-butyrylamino)-8-oxo-3-vinyl-5-thia-l-azabicyclo (4.2.0)oct-2-ene-2-carboxylic acid 4-methoxyphenyl ester. The active methylene group in that product was then nitrosated with sodium nitrite. The initial product spontaneously tautomerizes to afford 7-(4-bromo-2-hydroxyimino-3-oxo-butyrylamino)-8-oxo-3-vinyl-5-thia-l-azabicyclo(4.2.0) oct-2-ene-2-carboxylic acid 4-methoxyphenyl ester. By the reaction of that compound with thiourea and then with trifluoroacetic acid was obtained (6R,7R)-7-(2-(2-amino-4-thiazolyl)glyoxylamido)-8-oxo-3-vinyl-5-thia-l-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid sodium nitrite, (Z)-oxime (Cefdinir sodium nitrile). 

Deamination of 3-amino derivative 23 with sodium nitrile in acetic acid gave 5,6-dimethylthieno[2,3-d]pyrimidin-4(3//)-one [85IJC(B)432]. Using the same reaction procedure, 3-amino derivative 82b (R = NH2) was converted into the thieno[2,3-d]pyrimidine-2(l//)-thione 78b (90JHC269). 

Sodium Nitrile saluialBd. 11 2a 90 9 0 102.3 BF Good. TompRilo pkpB... 

I rvparallon. A inixtiirc of 0.5 mole of Niilfiinilic iiciil and 0.25 mole of sodium ciirhomitc is dissolved in 5(M) ml. of wider iind Ihc solution is cooled to 15", ireated with a soliilion of 0.54 mole of sodium nitrile in 100 ml. of water, iiiul poured into II inixliirc of 1.25 moles of hydrochloric acid and hOO g. of ice. I lie soliilion. fmni... 

Synthesis, stmcture and protective properties of tetra sodium nitrile-tris-methylene phosphonate zincate tridecahydrate Na4[N(CH2P03)3Zn]-13Hp... 

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