Sodium 3-naphthalenesulphonate

The bulb of the thermometer, which is maintained in position by a bored cork, dips into a layer of oil 1 cm. thick. (See Fig. 55.) Goggles and gloves must be worn. As soon as the temperature has reached 280° the sodium naphthalenesulphonate is added rather rapidly with stirring heating is continued with a somewhat smaller flame and the temperature is maintained between 260° and 280°. 

Reductive desulphonation of naphthalenesulphonic acids is also observed [84]. The 1-sulphonic acid substituent in a wide range of sulphonated naphthylamines is removed by reduction at mercury in aqueous sodium hydroxide [85], Reductive... 

Sodium l naphthalenesulphonate [85-47-2] M 230.2. Recrystd from water or aqueous acetone [Okadata et al. JACS 108 2863 1986. ... 

Sodium 2>naphthalenesulphonate [532-02-5] M 230.2. Crystd from hot 10% aqueous NaOH or water, and dried in a steam oven. 

Tamoxifen 352, a non-steroidal anti-estrogen, employed for treatment of breast tumors which are estrogen receptor positive488, has been labelled with 131l489 for imaging and detection of breast tumors (equation 224). The reaction of diazonium salts (355, tetraphenylb-orate and 2-naphthalenesulphonate) with equimolar aqueous sodium iodide without catalysts or in the presence of Cu catalysts gave 353 in 6-10% yield only489. 

The reactions of the naphthalenesulphonic adds are similar to those given above under benzenesulphonic add. It is still to be mentioned that the a-add is converted into the /8-add by heating with concentrated sulphuric add to almost 2000 a reaction which is explained by the feet that the sulphonic add decomposes in the small amount of water always present, into naphthalene and sulphuric acid, and that the former is then sulphonated to the /8-add at the higher temperature (2000). The sulphonation of naphthalene to the a-and /3-adds is carried out on the large scale in technical operations, since when fused with sodium hydroxide these adds yield naphthols of great importance for the manufacture of dyes. The next preparation deals with this reaction. 

Sodium hydroxide Methylenebis(naphthalenesulphonic acid) sodium salt Sulphur... 

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