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Small molecule protein binding sites

Target-Based Virtual Screening on Small-Molecule Protein Binding Sites... [Pg.411]

Recently, imino sugars have found application as active site specific chaperones (ASSC) for the treatment of lysosomial storage disorders.65 An ASSC is a small molecule that bind the catalytic domain of an enzyme inducing the regeneration of the active conformation of misfolded proteins. [Pg.275]

Where are the nuclei . This is nob just a question of equilibrium shape as measured by n.m.r./ x-ray or neutron spectroscopy/ but also concerns what possible shapes the molecule can asscune as it interacts with its partner in general/ what flexibility it possesses. Flexibility is clearly a property of both small molecules and the protein binding sites. [Pg.174]

See other pages where Small molecule protein binding sites is mentioned: [Pg.606]    [Pg.526]    [Pg.362]    [Pg.526]    [Pg.1009]    [Pg.352]    [Pg.183]    [Pg.184]    [Pg.283]    [Pg.270]    [Pg.216]    [Pg.97]    [Pg.259]    [Pg.276]    [Pg.25]    [Pg.321]    [Pg.412]    [Pg.63]    [Pg.224]    [Pg.606]    [Pg.767]    [Pg.380]    [Pg.252]    [Pg.222]    [Pg.51]    [Pg.111]    [Pg.283]    [Pg.80]    [Pg.1009]    [Pg.42]    [Pg.6222]    [Pg.130]    [Pg.18]    [Pg.272]   


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Binding molecules

Binding small molecules

Protein small molecule

Protein small proteins

Proteins binding sites

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