Skin hemorrhage intravenous

Skin Cutaneous reactions associated with intravenous immunoglobulin are uncommon, but include pruritus, non-specific eruptions, erythema, urticaria, eczema, pompholyx, pete-chiae, and skin hemorrhage [53, 54 , 55 , 57 , 59 ]. 

SAFETY PROFILE Poison by ingesdon, skin contact, subcutaneous, and intravenous routes. Human systemic skin effects by skin contact hemorrhage, allergic dermadds, and primary irritation. Mutadon data reported. When heated to decomposidon it emits toxic fumes of NOx. See also AMINES. 

A 52-year-old woman was given vancomycin 1 g intravenously bd and within 12 hours developed a generalized pruritic maculopapular rash (83). Over the next few days, the lesions progressively worsened and transformed into hemorrhagic and non-hemorrhagic vesicles and bullae. Mucosal surfaces, palms, and soles were spared. The skin lesions completely healed without scarring within 2 weeks of vancomycin withdrawal. There was no recurrence 5 months later. 

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