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Skeletal muscles experimental model

Bradykinin stimulates natriuresis and, through stimulation of prostaglandin synthesis, inhibits the actions of antidiuretic hormone (ADH), thereby inhibiting water retention. Bradykinin further improves insulin sensitivity and cellular glucose utilization of skeletal muscle cells in experimental models. This, however, appears not to be relevant in the clinical context. [Pg.10]

Lithium was reported to diminish tau and AP pathologies in various experimental models of Alzheimer disease (reviewed in [253]), but its clinical efficacy in treating Alzheimer disease patients is not established. In a transgenic mouse model whose skeletal muscle bears some aspects of IBM muscle fibers, lithium was reported to decrease tau phosphorylation through decreasing activity of GSK-3P [254]. [Pg.134]


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See also in sourсe #XX -- [ Pg.753 ]




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Skeletal muscle

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