Size Exclusion Chromatographic ISEC Analysis of Solvent Wetted Polymer Supports

Inverse Size Exclusion Chromatographic (ISEC) Analysis of Solvent Wetted Polymer Supports 

Unfortunately there are no routine methodologies for evaluating the morphology of solvent wet resins at least in terms of generating quantitative data on surface area and pore size distribution. It is possible to use the adsorption of a suitable molecule from the solvent, assume monolayer coverage and an molecular area for the molecule, and hence compute a surface area. This technique has been used in assessing the surface area of e.g. sihca and alumina but has not proved valuable in the case of resins. 

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