Sinularia capillosa

The typical secondary metabolites of soft corals are diterpenoids, although some species also produce sesquiterpenoids. The sesquiterpene portion of furoquinol (Structure 2.102) is labeled by [2-3H]mevalonolactone in Sinularia capillosa,m while Heteroxenia sp. converts acetate and meva-lonate into cubebol (Structure 2.103) and clavukerin A (Structure 2.104).188 In contrast, acetate is used for cetyl palmitate synthesis in Alcyonium molle, but not for de novo diterpene biosynthesis.188... 

Gopichand et al. (407) isolated two new acyclic sesquiterpene hydrocarbons (483) and (484) from the gorgonian Plexaurella grisea as well as (-h)-a-santalene (485), which is well-known from terrestrial source. Bowden et al. (408) described new sesquiterpene furans from Sinularia capillosa and S.firma, all of which were structurally related. The furanoquinol (486) was the predominant isolate and was accompanied by the related furanoquinone (487) which may be an artifact. In addition they found the methylfurans (488-492), the furan methyl esters (493-496), and the furan carboxylic acids (497-500). A related methylfuran (501) has been obtained from the Mediterranean alcyona-cean, Alcyonum palmatum (409). 

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