Single-probe method

The other molecular probe method is the single-probe method (SP method), which is separately proposed by Avnir and Jaroniec,93 and Pfeifer et al.108-112 In the SP method, a single adsorption isotherm is analyzed using a modified FHH theory. The FHH model was developed independently by Frenkel,113 Halsey,114 and Hill,115 and describes the multilayer adsorption coverage. Since the SP method uses only one probe molecule, this method is more convenient than the MP method. However, there are many theoretical limitations in applying the SP method to determination of the surface fractal dimension. Therefore, it is really necessary to discuss whether the SP method is an adequate tool to investigate the surface fractal dimension or not before applying the SP method to certain system. 

The other molecular probe method is the single-probe method (SP method), which is separately proposed by Avnir and Jaroniec,93 and Pfeifer eta/.108-112 In the SP method, a single... 

F,SP Surface fractal dimension determined by single-probe method using gas adsorption the... 

Using the single-probe method, a 30-base sequence common to five strains of coli could be detected using the latex-based labels, with detection limits of 25 fM (silver nanoparticles on hollow capsules) [105] and 0.5 fM (gold nanoparticles on latex) [131], as shown in Fig. 8.18. The lower detection limit for the second method... 

Compound 20 was reported to be the first highly conductive (14 S cm on compaction pellet sample) single-component molecular metal different from the dithiolate-type however, the conductivity was measured by a two-probe method and no SQUID response was observed for 200 K > T > 5 K [78]. 

In summary, the presented results demonstrate the capacity of combining IR-pump-probe methods with calculations on microsolvated base pairs to reveal information on hidden vibrational absorption bands. The simulation of real condensed phase dynamics of HBs, however, requires to take into account all intra- and intermolecular interactions mentioned in the Introduction. As far as DNA is concerned, Cho and coworkers have given an impressive account on the dynamics of the CO fingerprint modes [22-25]. Promising results for a single AU pair in deuterochloroform [21] have been reported recently using a QM/MM scheme [65]. 

As a single cell technique capable of achieving large deformations, the method complements the pressure probe method. It should be valuable in studies of how plant cell mechanical properties are affected by the molecular composition and structure of the wall, and how these are affected by food processing operations. 

Resistivity Measurements. The measurements by the Cornell group have all been made on single crystals by a potential-probe method, the details of which have been reported (32). Typical results are presented graphically in Figure 3. 

One of the primary compounds that the cell membrane is composed of is DMPC, because of its surface activity caused by a hydrophobic zwitterion. A hydrodynamic model of the DMPC membrane can evaluate the intrinsic viscosity (r]i) of the surfactant monolayer, eliminating the contribution of the viscosity of dodecane and aqueous phases. The T]i values listed in Table 10.1 are about 2-4 times higher than the apparent i. The maximum t]i value, 0.75 Pa s, is comparable to that of a common viscous liquid such as glycerin (0.945 Pa s). This study demonstrated that a single molecule probing method could successfully measure the hydrodynamic properties of the interface. 

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