Single focusing mass analysers

Fto. 1. Block diagram of a combination of gas chromatograph-single focusing mass spectrometer (LKB 9000). A-B = analyser tube E = electrode for monitoring a part of the total ion current 5 = ion source exit slit 2 cdlector dit MID = multiide ion detector control for monitoring ions of high mass (Af j), middle mass (M2) and low mass (M3). 

Fig. 5 Statistical evaluation of LC-MS-based methods for tropane alkaloids referred in this chapter. (a) Relative frequency of ionization methods. +APCI positive atmospheric pressure chemical ionization, +ESI positive electrospray ionization, FAB fast atom bombardment, +TSP positive thermospray, (b) Relative frequency of scan modes used. MS full scan MS, MS/MS tandem mass spectrometry (product ion scan), MRM multiple reaction monitoring, SIM selected ion monitoring, (c) Relative frequency of mass analysers used. EBQtQ2 double focusing sector field mass spectrometer, IT ion trap, QqQ triple quadrupole, SQ single quadrupole. Considered publications were found by PubMed data-based search and references cited in these articles...

Half a century ago a mass spectrometer was a single focusing magnetic sector instrument its console contained a clock to facilitate reproducible measurements, since it was mainly used for analyses of hydrocarbon mixtures. Very often an analog computer was associated with the instrument in order to permit the solution of the linear equations needed to... 

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