Ion chromatography single column

S. S. Chen, H. Lulla, F. J. Sena, and V. Reynoso, Simultaneous determination of potassium nitrate and sodium monofluorophos-phate in dentifrices using single column ion chromatography, J. Chromatogr. Sci., 23 355 (1985). 

L. Svoboda and U. Schmidt (1997). Single-column ion chromatography of linear polyphosphates. 

Fig. 2 Conductivity detection of anions in nonsuppressed (single column) ion chromatography using an eluent of (a) low background conductance (direct detection) and (b) high background conductance (indirect detection). The direction of the arrow indicates the increase of conductivity.

Nonsuppressed single-column ion chromatography (SCIC) was introduced in 1979 by Gierde and coworkers, based on a two-principal innovation ... 

Single-column ion chromatography offers the advantage of not requiring special equipment for suppression. It is a somewhat less sensitive method of determining anions than are suppressor column methods, however. 

Single-column ion chromatography measurements afford a retention time of... 

Electronic suppression is possible if the eluent is properly chosen for extra-low conductivity which is e.g. the case with phthalate buffers. The detector must be able to compensate for the background conductivity by its electronics. Such a set-up gives good calibration linearity over a wide range but its detection limit is rather poor. For historical reasons it is also termed single-column ion chromatography. 

C. McCrory-Joy, Single-column ion chromatography of weak inorganic acids for materials and process characterization. Anal. Chim. Acta. 181,277,1986. 

H.C. Mehra and WT. Frankenberger. Jr., Simultaneous determination of selenate and selenite by single-column ion chromatography, Chromatographia. 25,585.1988. 

By choosing an eluent that does not dissociate strongly it is possible to eliminate the suppressor column. Such compounds as phenol, pK, = 1.3 x 10 , or phthalic acid, K, = 1.3 x 10 K,2 = 3.9 x 10, are examples. When compounds of this type are used the system is called single column ion chromatography (SCIC). Table 24-2 lists some of the other common eluents for anions. 

Karlson, U. and Frankenherger, W. T. Jr., Single column ion chromatography of selenite in soil extracts, Anal. Chem., 58, 2704-2708, 1986. 

Pentchuk j, Haldna U and Ilmoja K (1986) Determination of nitrate and chloride ions in food by single-column ion chromatography. J Chromatogr 364 189-192. 

Figure 12.5 Separation of a seven-anion standard with single-column ion chromatography. Column [Chromatographic conditions IC-Pak Anion HR, 4.6 mmx7S mm. Waters Corp. Eluent borate/gluconate. Sample seven-anion standard (1) fluoride (2) bicarbonate (3) chloride (4) nitrite (S) bromide (6) nitrate (7) phosplmt (8) suUite. Detection conductivity. (Qiromatogram courtesy of Waters Corp.)...

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