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Simulation of chromatin stretching

Cui and Bustamante [66], Bennink et al. [43], Brower-Toland et al. [42], and Leuba and Zlatanova (unpublished results) have reported single molecule stretching [Pg.411]

While structural transitions at the level of nucleosomes are still outside the scope of current models, applying a constant force to both ends of the liber allows to simulate the low end of the force-extension curve. First results from our own work (Aumann, Caudron, Wedemann, and Langowski, manuscript in preparation) are shown in Fig. 5. In this particular example, a nucleosome repeat of 200 bp and a linker DNA length of 11 bp was used. [Pg.412]


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Chromatin

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