Simple reactions in liposomes

Other charged species cannot go through bilayer 

The (charged) reaction product is blocked inside the vesicle 

There are several other ways to entrap solutes inside the liposomes, and the entrapping efficiency depends on the structure of liposomes (small unilamellar, large unilamellar, multilamellar, vesicles, etc.) and from the technique for liposome preparation (Roseman etal., 1978 Cullis etal., 1987 Walde and Ishikawa, 2001). 

Also the surface of liposomes can be utilized for facilitating chemical reactions. One example is the liposome-aided synthesis of peptides already mentioned in Chapter 4 (Blocher et al., 2000 2001). In this case, the binding of hydrophobic 

Going back to the entrapment into the water pool, work on enzymes in liposomes has been and is an active research field. Most of the work presented in the literature concerns the entrapment of one enzyme at a time. In particular, the excellent review by Walde and Ischikawa, 2001 provides a rich account and discussion of the various techniques used to incorporate enzymes inside liposomes, and their possible applications in chemistry, medicine, and industry. Table 10.1 is a modification and simplification of one of their tables (Walde and Ischikawa, 2001, Table 6). This 

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