Significance of Imperturbable Surface in Biocompatibility

The imperturbability of a surface is a vitally important factor, in the author s view, for the biological compatibility of artificial surfaces. The imperturbability of a surface could be attained by (1) molecular configuration of macromolecule, such as the case of poly(oxyethyle) (POE), or (2) immobile network structure in the top surface, such as the case of the tight network of luminous chemical vapor deposition (LCVD) nanofilm. 

Adopting the term surface configuration, those observations by Langmuir could be rephrased so that the general surface properties could be addressed by the same term. 

The surface properties of a polymer are determined by the surface configuration rather than the configuration of a macromolecule. 

Surface configuration changes responding to the conditions under which a surface exists. This is the basic phenomenon that is observed under the topics of 

Surface configuration can be fixed by chemical reactions. This is the foundation for the creation of an imperturbable surface. LCVD processing is extremely useful in this particular aspect. 

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