Signal transduction mammalian cells

This section explains how genetic studies with Drosophila and Caenorhabditis elegans have contributed to the discovery of the Ras signal-transduction pathway operative in mammalian cells. 

Gall, C. von, Stehle, J. H. Weaver, D. R. (2002). Mammalian melatonin receptors molecular biology and signal transduction. Cell Tiss. Res. 309, 151-62. 

Plants respond to many environmental stimuli, and employ hormones and growth factors to coordinate the development and metabolic activities of their tissues. Plant genomes encode hundreds of signaling proteins, including some very similar to those used in signal transductions in mammalian cells. 

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