Sialic acids biological roles

R. Schauer, S. Kelm, G. Reuter, P. Roggentin, and L. Shaw, Biochemistry and role of sialic acids, in A. Rosenberg, (Ed.), Biology of the Sialic Acids, Plenum Press, New York, 1995, pp. 7-67. 

Emphasis will be given to the metabolism (see Sections V and VII) of sialic acids, which is connected with the biological roles of these compounds. 

Exact analysis of sialic acid is required in biologieal experiments where the biological role of sialic acid is frequently studied with the aid of sialidases, and the amount of sialic acids released is determined. This is also important for periodate oxidation studies on biological systems, where modification of sialic acids by periodate is only assumed, but chemical analysis of this effect by isolation and analysis of the modified sialic acids is seldom performed. These uncertainties in determinations of sialic acid can be overcome by the purification procedures already described. Furthermore, it must be stressed that unequivocal determination of the structure of a sialic acid, especially... 

A. Rosenberg and C. L. Schengrund, Biological Roles of Sialic Acids, Plenum Press, New York, 1976. 

Jeanloz, R. Codingten, J. The biological role of sialic acid at the surface of the cell. In Biological Roles of Sialic Acids Rosenberg, A. Schengrund, C. Eds. Plenum Press New York, NY, 1976, 201-238. 

Schauer R, Kelm S, Reuter G, Roggentin P, Shaw L (1995) Biochemistry and role of sialic acids. In Rosenberg A (ed) Biology of the sialic acids. Plenum, New York, p 7 Schauer R (1982) AdvCarbohydr Chem Biochem 40 131... 

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