SIACX

SIACX, or succinimidyl-6-((((4-(iodoacetyl)amino)methyl)cyclohexane-l-carbonyl)amino) hexanoate, is an analog of SIAC that contains an additional aminohexanoate spacer group next to its NHS ester end (Invitrogen). The result is the creation of an approximately 16-atom spacer arm between conjugated molecules. All other properties of SIACX are similar to SIAC. 

Conjugation reactions done with SIAC or SIACX are usually multi-step procedures similar to the protocol described for SIAB, previously. 

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