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ShRNA library

HT-RNAi screens of mammalian cells primarily use either short interfering RNA (siRNA) or small-hairpin RNA (shRNA) libraries. Although there are similarities between the two platforms, screening using siRNA libraries has the advantages of having minimal... [Pg.89]

Silva, J.M. et al. 2005. Second-generation shRNA libraries covering the mouse and human genomes. Nat. Genet. 37, 1281-1288. [Pg.167]

Another commonly used RNAi screeiung method uses pooled shRNA library and it is also known as RNAi barcode screens. shRNA libraries are mainly used in this pooled base assays and it is a promising approach to identify novel targets for cancer therapy. [Pg.412]

See other pages where ShRNA library is mentioned: [Pg.261]    [Pg.132]    [Pg.243]    [Pg.258]    [Pg.158]    [Pg.161]    [Pg.242]    [Pg.3154]    [Pg.1118]    [Pg.1118]    [Pg.125]    [Pg.411]    [Pg.411]    [Pg.412]    [Pg.261]    [Pg.132]    [Pg.243]    [Pg.258]    [Pg.158]    [Pg.161]    [Pg.242]    [Pg.3154]    [Pg.1118]    [Pg.1118]    [Pg.125]    [Pg.411]    [Pg.411]    [Pg.412]    [Pg.131]    [Pg.132]    [Pg.132]    [Pg.199]    [Pg.296]    [Pg.158]    [Pg.159]    [Pg.161]    [Pg.274]    [Pg.3154]    [Pg.112]    [Pg.257]    [Pg.1118]    [Pg.410]    [Pg.413]    [Pg.112]    [Pg.43]   
See also in sourсe #XX -- [ Pg.411 ]



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