Shaped Pulses and Other Homonuclear Experiments

The excitation sculpting method was expended to the selective inversion of z-magnetisation. The method utilises DANTE train of hard pulses combined with gradient suppression of transverse magnetisation. Application of the selective inversion to z-magnetisation reduces relaxation loses and extends selective methods to larger molecule. Use of shaped pulses in DANTE train produces band-selective inversion. The proposed inversion method can be 

Signal separation in NMR spectra is not restricted to NMR parameters. Other physical properties can be used to create indirect spectral dimensions. He et al. reported 3D EP COSY experiment which utilises electrophoretic migration rates to separate resonances from individual components in mixed solutions. Additional modulation of COSY resonances is introduced in the experiment by a stepwise increase of the electric field. Due to the presence of gradient pulses in the sequence the amplitude of the resonances has a cosine dependence on the field strength with the period depending on the electrophoretic mobility. In the processed spectra, COSY spectra of individual components are observed in separate planes. 

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