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Serotonin receptors disease associations

Many studies have shown associations of SNPs in such genes as the serotonin 5-HT and 5-HT receptors, genes and the histamine receptor gene, not to the phenotype of disease severity, but to phenotypes such as drug response or nonresponse (97). For example, the S-HT receptor gene variants and the variant that encodes the Cys22Ser receptor have been associated with altered responses to clozapine (97). [Pg.148]

Assal F, et al. Association of the serotonin transporter and receptor gene polymorphisms in neuropsychiatric symptoms in Alzheimer disease. Arch Neurol 2004 61(8) 1249-1253. [Pg.85]

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