Seronegative spondyloarthropathies

The NSAIDs have a number of commonalities. Although not all NSAIDs are approved by the FDA for the whole range of rheumatic diseases, most are probably effective in rheumatoid arthritis, seronegative spondyloarthropathies (eg, psoriatic arthritis and arthritis associated with inflammatory bowel disease), osteoarthritis, localized musculoskeletal syndromes (eg, sprains and strains, low back pain), and gout (except tolmetin, which appears to be ineffective in gout). 

The first question to ask to the patient with knee complaints is whether the symptoms are chronic or acute. In chronic abnormalities, the possible occurrence of systemic articular disorders such as rheumatoid and psoriatic arthritis, seronegative spondyloarthropathy, and degenerative and metabolic disorders should be considered. Close coop-... 

The tibialis posterior tendon is the most commonly injured tendon on the medial side of the ankle. Its rupture is typically encountered in middle-aged obese women or as a result of systemic disease, such as rheumatoid arthritis or seronegative spondyloarthropathy (Johnson 1983). Acute fractures of the ankle may also be responsible for some cases of rupture of this tendon. In most cases, tibialis posterior tendon tears occur around the medial malleolus, but they may also be encountered at the navicular insertion. Rupture of the is frequently overlooked clinically because it often develop with no history of trauma. Initially, the patient complains of pain and swelling around the affected tendon. Then, as the severity of the lesion gradually progresses toward rupture elongation, gradual collapse... 

Chronic posterior ankle pain may also be related to bursal pathology, which may occur as an isolated disorder but is more often secondary to inflammatory disorders, such as rheumatoid arthritis and seronegative spondyloarthropathies, or repetitive trauma, usu-... 

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