Sequence-Specific Recognition of Double Helical Nucleic Acids

1 Sequence-specific Recognition of Double Helical Nucleic Acids 

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Seeman, N.C., Rosenberg, J.M., Rich, A. Sequence-specific recognition of double helical nucleic acids by proteins. Proc. Natl. Acad. Sci. USA 73 804-809, 1976. 

At present, there are only a few cases known of sequence-specific hydration of double helical nucleic acids. With the availability of more crystal structure data, new information concerning sequence-specific hydration is expected. This kind of hydration can have an influence on the recognition of nucleic acids by proteins, and is therefore of great interest. 

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