Sequence Databases Beyond NCBI

Although it may appear from this discussion that NCBI is the center of the sequence universe, many specialized sequence databases throughout the world serve specific groups in the scientific commimity. Often, these databases provide additional information such as phenotypes, experimental conditions, strain crosses, and map features. The data are of great importance to these subsets of the scientific commimity, inasmuch as they can influence rational experimental design, but such types of data do not always fit neatly within the confines of the NCBI data model. Development of specialized databases necessarily ensued, but they are intended to be used as an adjunct to GenBank, not in place of it. It is impossible to discuss all of these kinds of databases here, but, to emphasize the sheer number of such databases that exist. Nucleic Acids Research devotes its first issue every year to papers describing these databases (cf. Baxevanis, 2001). 

Standard Name HHOl Click on map for expanded view  

Gene Product histone HI 1 Gene Info 11 Viev 1  

Phenotype Null mutant is viable other phenotype Increased basal expression of a CYCl-lacz reporter gene nuclear localization of a Hhol-GFP fusion protein Retrieve Sequences  

External Links MIPS 1 YPD 1 Entrez Protein Entrez Neighbors PIR-DE PIR-JP PIR-US Comparison Resources 1 Worm Homologs 1 1 Viev I  

---