Separation of Peptides by Gel Permeation, Ion-Exchange, and Polar Adsorption HPLC

SEPARATION OF PEPTIDES BY GEL PERMEATION, ION-EXCHANGE, AND POLAR ADSORPTION HPLC 

In this section peptide separation by gel permeation, normal-phase adsorption, ion-exchange, and liquid-solid adsorption HPLC will be considered. Compared to reversed-phase HPLC, these elution modes have attracted considerably less interest for peptide separations. This is due to a number of factors arising from the diverse characteristics of the solutes 

Gel Permeation and Normal-Phase Liquid-Liquid HPLC of Peptides 

With present bonding technology, it is not feasible to produce hydrophilic phases which satisfy all these criteria. The strong interactive adsorption of 

Besides the bonded diol or epoxy type of hydrophilic stationary phase, a number of other types of bonded silica supports of varying phase 

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