Sensing and Transduction

Mechanosensing is postulated to involve many different cellular and extracellular components. Mechanical forces cause direct stretching of protein-cell surface integrin binding sites that occur on all eukaryotic cells. Stress-induced conformational changes in the extracellular matrix may alter integrin structure and lead to activation of several secondary messenger pathways within the cell. Activation of these pathways leads to altered reg- 

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Regarding biosensor production, its marketing is in competition with many chemical analytical systems as well as conventional laboratory techniques. Most of the patents are presented by scientific institutions as biosensor prototypes without a real potential for commercialisation. The insritutions should stricdy collaborate vwth industries to define the properties of a real marketable product. Econontical and technical problems should be overcome, together with the manufecture of the sensing and transductions components and their increased reliability and stability. 

Key words semiconducting metal oxide (SMOX), sensing and transduction of SMOXs, p- and n-type MOXs, conduction mechanism, modelling, measurements taken in working conditions. 

Sensing and transduction for p- and n-type semiconducting metal oxides... 

Barsan, N., Simion, C., Heine,T., Pokhrel, S. and Weimar, U. (2010) Modehng of sensing and transduction for p-type semiconducting metal oxide based gas sensors . Journal of Electroceramics, 25(1), 11-19, DOI 10.1007/sl0832-009-9583-x... 

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