Self-complementary hexamer

The NMR structure of a self-complementary hexamer RNA duplex incorporating an isoguanosine-isocytidine base pair has been solved. Whilst the struc-... 

In 1986 von Kiedrowski reported the autocatalysis of a palindromic nucleotide hexamer. Unlike simple (self-)complementary hydrogen bonding sequences, DNA can have both template and complementary strands [39], In this example the components were CCG (A), protected at the 5 -terminus and activated at the 3 -phosphate terminus, and CGG (B), protected at the 3 -t.crminus. A doubly protected template,... 

The Rayner group has reported several examples of the use of dynamic nucleic acid decoration for stabilizing structures of interest. In the first of these, described in 2004 [45], a mixture consisting of a self-complementary DNA hexamer bearing a 2 -amino-2 -deoxyuridine at the 3 -terminus with a pool of three aldehydes (51-53, Fig. 19) and sodium cyanohydride was generated. Analysis of aliquots of the... 

As described in Sect. 2, imidazolyl zinc porphyrin is an excellent candidate for self-complementary coordination due to its extremely large stability constant. In order to arrange these complementary coordination units into a hexam-eric macrocycle, two imidazolyl zinc porphyrins were connected through an m-phenylene group to fix the angle at 120 , offering a gable porphyrin... 

The head of each spectrin chain interacts with the head of the complementary chain of another heterodimer. In the tetramer, there are paired interactions (Fig. 5-31), while in higher oligomers, a closed loop is formed, as the head region is quite flexible. This is shown for the hexamer in Fig. 5-39, but this self-association may continue indefinitely. 

Figure 31 (a) A cyclic hexamer formed by the self-assembly of preorgahized dendritic monomers (54) containing complementary DDA and AAD hydrogen-bonding arrays [107,108] (b) a cyclic hexamer formed by self-assembly of a ditopic monomer (55) containing ureidopyridopyrimidine 6 [26]. 

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