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Selective receptor modulators

Smith CL, O Malley BW (2004) Co-regulator function a key to understanding tissue specificity of selective receptor modulators. Endocr Rev 25 45-71... [Pg.90]

Top S, Vessieres A, Cabestaing C, Laios I, Leclercq G, Provot C, Jaouen G (2001) Studies on organometallic selective receptor modulators (SERMs). Dual activity in the hydroxy ferrocifen series. J Organomet Chem 637 500-506... [Pg.111]

Selective oestrogen receptor modulators (SERMs, e.g. Raloxifene) Calcitriol and analogues (limited use)... [Pg.280]

Sex Steroid Receptors Androgen Receptor, Estrogen Receptors, Progesterone Receptor Selective Sex-steroid Receptor Modulators... [Pg.393]

Selective Sex Steroid Receptor Modulators Receptor Modulators... [Pg.469]

Selective estrogen receptor modulators (SERMs) are synthetic compounds with partially agonistic and partially antagonistic estrogenic properties. In bone, SERMs inhibit bone resorption via the mechanisms known for estrogens. Major SERMs are tamoxifen, a triphenylethylene compound, and raloxifene. In postmenopausal women, the latter has been shown to prevent bone loss and to reduce fracture risk by 40%. [Pg.1112]

Selective progesterone receptor modulators (SPRMs, mesoprogestins) are progesterone receptor (PR) ligands... [Pg.1112]

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Selective receptors

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