Selection through Molecular Recognition of an External Template

Selection through Molecular Recognition of an External Template 

One of the most appealing applications of DCC is the possibihty to determine from a complex mixture the best binder of a given target molecule. Upon addition of the template molecule to the library, the means of identifying an efficient binder is through its overexpression in the library. Therein the advantage of the approach is clear-not only is the desired molecule identified, but it is synthesized in preference to library members with a lesser affinity for the target molecule. In a particularly effective library, the addition of a template to the mixture may induce all the library material to convert to just one favored species. 

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