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Selectin inhibitors design

Many of the individual topics addressed in the present chapter have been discussed in the context of excellent specialist reviews. Some of these are cited in the respective sections. Wong and his associates have prepared a comprehensive review entitled Selectin-Carbohydrate Interactions from Natural Ligands to Designed Mimics which provides a complete survey of the literature dealing especially with the medicinal chemistiy aspects of selectin inhibitor design treatment of this aspect has therefore been restricted to a few representative examples in the present article. Vcstwcbcr has edited a comprehensive monograph entitled The Selectins Initiators of Leukocyte Endothelial Adhesion. [Pg.214]

Based on this lead, several academic and industrial groups have designed selectin inhibitors with improved pharmacodynamic and pharmacokinetic properties. The major goals (besides... [Pg.853]


See other pages where Selectin inhibitors design is mentioned: [Pg.388]    [Pg.414]    [Pg.388]    [Pg.414]    [Pg.237]    [Pg.863]    [Pg.865]    [Pg.866]    [Pg.351]    [Pg.385]    [Pg.415]    [Pg.854]    [Pg.856]    [Pg.857]    [Pg.644]    [Pg.644]    [Pg.648]    [Pg.663]    [Pg.36]    [Pg.222]    [Pg.225]    [Pg.240]    [Pg.105]    [Pg.256]    [Pg.323]    [Pg.279]    [Pg.867]    [Pg.2100]    [Pg.214]    [Pg.315]    [Pg.343]    [Pg.375]    [Pg.386]    [Pg.394]    [Pg.262]    [Pg.858]    [Pg.306]    [Pg.177]    [Pg.645]    [Pg.253]    [Pg.1003]    [Pg.49]   
See also in sourсe #XX -- [ Pg.415 ]




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