Seizures cyanide-induced

Yamamoto, H.-A. (1995). A hypothesis for cyanide-induced tonic seizures with supporting evidence. Toxicology 95 19-26. 

Yamamoto, H.-A., Tang, H.-W. (1996). Antagonistic effect of melatonin against cyanide-induced seizures and acute lethality in mice. Toxicol. Lett. 87 19-24. 

Lactic acidosis Cyanide, carbon monoxide, ibuprofen, isoniazid, metformin, salicylates, valproic acid any drug-induced seizures, hypoxia, or hypotension... 

Remove animal from the affected area. Do not induce vomiting due to the rapid progression of the clinical signs and potential for seizures, coma, or apnea. One gram of activated charcoal will bind 35 mg of cyanide and activated charcoal may be beneficial if administered immediately after ingestion (Lambert et al, 1988). Irrigate eyes for at least 15 to 20 min with tepid water. Bathe animals thoroughly with soap and water. 

Bitner, R.S., Kanthasamy, A., Isom, G.E., and Yim, G.K.W., Seizures and selective CA-1 hippocampal lesions induced by an excitotoxic cyanide metabolite, 2-iminothia-zolidine-4-carboxylic acid, NeMrotoxico/o y, 16,115, 1995. 

Remove animals from the affected area. Do not induce vomiting due to the rapid progression of the clinical signs and potential for seizures, coma, or apnea. A gram of activated charcoal will bind 35 mg of cyanide. 

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