Secretin physiologic functions

Physiological functions. Secretin stimulates the production of bicarbonate and water alone. It flushes out the enzymes already present in the ducts. It exerts only a slight stimulating influence upon the secretion of water from the liver (Jonson 1964). 

Somatostatin has been found to inhibit the secretion of various other hormones such as thyrotropin, gastrin inhibitory peptide (GIP), vasoactive intestinal peptide (VIP), pancreozymin, secretin, motilin, gastrin, renin, ACTH in patients with ACTH-secreting pituitary adenoma and ACTH-secretion vitro and to effect exocrine pancreatic function and various GI functions. "21 The physiological significance of these findings is not clear at the present time. 

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